Program | 38th International Specialised Symposium on Yeasts (ISSY38)

12:00-18:00

Registration

15:30-18:00

OPENING CEREMONY
Chair: Adrianna Skoneczna & Zbigniew Lazar

16:00-17:00

'Yeast mating-type switching: a paradigm for studying the repair of a broken chromosome'
James Haber

17:00-18:00

'Insights from the diversity of antifungal drug tolerance responses'
Judith Berman

18:00-21:00

Get together

08:30-09:20

'Using yeast to study the ubiquitin-proteasome system'
Mark Hochstrasser

09:20-10:10

DECIPHERING OF MOLECULAR MECHANISMS OF EUKARYOTIC CELLS WITH YEAST I
Chair: Martin Kupiec & Joanna Kufel

09:20-09:40

'A genetic screen reveals the mechanisms that control sister chromatid cohesion'
Martin Kupiec

09:40-09:50

'WHO are you? – A new category of yeast mobile genetic elements at the borderline between homing and transposable elements'
Ludovic Monnin

09:50-10:00

'Unilateral ends-out gene targeting increases mistargeting'
Petar Tomev Mitrikeski

10:00-10:10

'Retrograde signalling in yeast Candida albicans'
Karolina Łabędzka-Dmoch

10:10-10:40

Coffee break

10:40-11:40

DECIPHERING OF MOLECULAR MECHANISMS OF EUKARYOTIC CELLS WITH YEAST II
Chair: Joanna Kufel & Martin Kupiec

10:40-11:00

'Non-canonical translation events in the yeast Saccharomyces cerevisiae'
Joanna Kufel

11:00-11:10

'The head, rather than the tail. Metabolic responses are tuned to RNA polymerase III de novo, non-coding RNA synthesis through the Dhh1-dependent pre-translational gene regulation'
Malgorzata Adamczyk

11:10-11:20

'Deciphering the diverse role of Gal4 transcription factor in the regulation of central carbon metabolism of Saccharomycetaceae yeasts'
Riccardo Milanesi

11:20-11:40

'Glucose induces selective autophagy of methanol-induced native and heterologous cytosolic proteins in the yeast Komagataella phaffii'
Andriy Sibirny

11:40-14:30

WARSAW TOUR

14:30-15:30

Lunch

15:30-16:20

'A genome-level screen identifies evolutionary conserved buffer genes that influence the phenotypic effect of de novo mutations in the yeast genome'
Kevin J. Verstrepen

16:20-17:00

YEAST SCREENS I
Chair: Brenda Andrews & Adrianna Skoneczna

16:20-16:30

'Cracking the code of the crabtree effect: enhancing S. cerevisiae's potential as a cell factory'
Samuel Hanon

16:30-16:40

'Time-resolved functional genomics using deep learning reveals a global hierarchical control of autophagy'
Jorrit Enserink

16:40-16:50

'Unravelling the natural complexity of protein secretion to develop novel yeast strains'
Dimitrios Konstantinidis

16:50-17:00

'Non-conventional yeast Mrakia as promising genus in low-alcohol beverages: a genome-based investigation unveiling the potential of Mrakia: a genomic perspective on its role in low-alcohol beverage innovation'
Benedetta Turchetti

17:00-17:30

Coffee break

17:30-18:40

YEAST SCREENS II
Chair: Brenda Andrews & Adrianna Skoneczna

17:30-17:50

'Yeast as an 'omni-tool' for functional genomics and systems biology'
Brenda Andrews

17:50-18:10

'Rewiring of genetic networks in yeast and other organisms'
Elena Kuzmin

18:10-18:20

''Small Volume – Big Problem': Culturing Yarrowia lipolytica in high-throughput micro-formats'
Ewelina Celińska

18:20-18:30

'Small molecule fitness profiling of diverse Saccharomyces cerevisiae strains using a novel CRISPR-Cas9 marker-less barcoded library'
Vivien Measday

18:30-18:40

'Identifying conserved aging regulators by high throughout lifespan screen in budding yeast'
Weiwei Dang

18:40-20:10

Poster session 1

09:00-09:50

'Making yeast more powerful: from the beginning to the future'
Xin-Qing Zhao

09:50-11:00

METABOLISM AND METABOLOMICS I
Chair: Diethard Mattanovich & Hiroshi Takagi

09:50-10:10

'Metabolic pathway design for efficient conversion of single carbon substrates into building block chemicals'
Diethard Mattanovich

10:10-10:30

'Hexokinase: the mysterious guardian of cellular energy'
Zbigniew Lazar

10:30-10:40

'Production of an extracellular polysaccharide from crude glycerol in industrial waste by the oleaginous yeast Rhodotorula toruloides: Uncovering a component responsible for the production'
Shigeyuki Kawai

10:40-10:50

'Metabolic engineering of Yarrowia lipolytica for the biosynthesis of vitamin A'
Jin Hou

10:50-11:00

'Bioconversion of sugarcane industry residues to oleochemicals engaging the non-conventional oleaginous yeast Pichia manshurica'
Wesley Cardoso Generoso

11:00-11:30

Coffee break

11:30-12:50

METABOLISM AND METABOLOMICS II
Chair: Ewelina Celińska & Diethard Mattanovich

11:30-11:50

'A novel proline metabolism found in Saccharomyces cerevisiae and its application to biotechnology'
Hiroshi Takagi

11:50-12:10

'Overcoming methanol toxicity for carbon-neutral overproduction of chemicals by enhancing cellular homeostasis and DNA repair'
Yongjin J. Zhou

12:10-12:20

'The dynamics of ergosterol biosynthesis in pathogenic Candida species'
Olga Heidingsfeld

12:20-12:30

'Nitrogen and phosphorus limitation as drivers of microbial lipid biosynthesis in waste hydrophobic media'
Katarzyna Wierzchowska

12:30-12:50

'When science meets production: some practical considerations'
Ildar Nisamedtinov

12:50-13:20

Coffee break

13:20-14:20

THE YOUNG RESEARCHERS FORUM
Chair: Ewelina Celińska & Diethard Mattanovich

13:20-13:50

'How to think about and do successful research - cliffnotes for graduate students and post-docs'
Terry Cooper

13:50-14:20

Workshop

14:20-15:30

Lunch

15:30-16:20

'Yeast as omni-tool to study host microbiome interactions'
Duccio Cavalieri

16:20-17:50

HUMANIZED YEAST IN HEALTH RESEARCH
Chair: Ľubomír Tomáška & Teresa Żołądek

16:20-16:40

'Expanding the yeast mitochondrial proteome by means of post-translational modifications'
ĽubomírTomáška

16:40-17:00

'Studies in yeast revealed a molecular mechanism of neurodegenerative diseases linked to MT-ATP6 mutations'
Róża Kucharczyk

17:00-17:10

'Genetic and environmental determinants of multicellular-like phenotypes in fission yeast'
Benjamin Heineike

17:10-17:20

'Cell size and its role in determining physiological efficiency: key player or side effect?'
Renata Zadrąg-Tęcza

17:20-17:30

'Yeast as an omni-tool to study and functionalize fungal peptide-GPCRs for synthetic cell-cell communication, biosensing and as future antifungal drug targets'
Sonja Billerbeck

17:30-17:40

'Accelerated screening of cell factory designs with G protein-coupled receptor-based yeast biosensors'
Emil Damgaard Jensen

17:40-17:50

'Regulation of arsenic-induced protein aggregate formation, processing, and clearance: insights from genome-wide image-based screening'
Jakub Masaryk

18:00-19:30

Poster session 2

18:30

ICY Meeting

09:00-09:50

'Continental scale variation of Saccharomyces yeasts'
Gianni Liti

09:50-10:50

YEAST IN POPULATION AND EVOLUTION MODELS
Chair: Cécile Neuvéglise & Matthias Sipiczki

09:50-10:10

'Evolution of mitochondrial genomes in interspecies Saccharomyces hybrids'
Matthias Sipiczki

10:10-10:20

'Model-guided predictive evolution of metabolic phenotypes'
Paula Jouhten

10:20-10:30

'Testing the mitochondrial prey hypothesis of apoptosis origin'
Szymon Kaczanowski

10:30-10:40

'Surprising sympatric divergence of the wild Saccharomyces cerevisiae in a Chinese subtropical forest region home to the oldest lineage of the yeast'
Feng-Yan Bai

10:40-10:50

'Dici: a new Tc1/mariner transposon reshaping the genome of Diutina catenulata'
Cécile Neuvéglise

10:50-11:20

Coffee break

11:20-13:00

FERMENTATION, FOOD AND BEVERAGES
Chair: Francisco Carrau & Zbigniew Lazar

11:20-11:40

'The shikimate pathway in Hanseniaspora vineae: a native eukaryotic model to enhance and study the biosynthesis of flavour bioactive compounds from aromatic amino acids'
Francisco Carrau

11:40-12:00

'Control of blue and green moulds on apples by antagonistic yeasts, and their effect on quality parameters during ambient and cold room storages'
Hüseyin Erten

12:00-12:10

'Genome-based exploration of alcohol acyltransferases for flavor formation in the food yeast Wickerhamomyces subpelliculosus'
Su Jin Yoo

12:10-12:20

'Yeast-assisted flavour improvement in pea protein-based yoghurt via controlled fermentation strategies'
Frederico Magalhães

12:20-12:30

'The role of yeast in the production of sauerkraut'
Paweł Satora

12:30-12:40

'Study of a potential CWI pathway like to S. cerevisiae in B. bruxellensis'
Maria Angelica Ganga

12:40-12:50

'Single cell proteins from yeast: From production to nutritional and functional potential'
Nathalie Gorret

12:50-13:00

'Evolution of maltose utilisation in wild Irish isolates of Saccharomyces eubayanus'
Sean Bergin

13:00-14:00

Lunch

14:00-15:10

YEASTS AS MOLECULAR FACTORIES I
Chair: Paola Branduardi & Rodrigo Ledesma-Amaro

14:00-14:20

'Sustainable food manufacturing using microbial metabolic engineering'
Rodrigo Ledesma Amaro

14:20-14:30

'Sustainable biosynthesis of natural sunscreens: Mycosporine-like amino acids and phytoene production in engineered yeasts'
Ji-Sook Hahn

14:30-14:40

'A survey for identification of endogenous Saccharomyces cerevisiae transporters capable of exporting succinic acid'
Andreea Perpelea

14:40-14:50

'Evaluating alternative metabolic engineering strategies for 3-hydroxypropionic acid production in Komagataella phaffii'
Pau Ferrer

14:50-15:00

'Converting lignocellulosic feedstocks to high-value lipophilic compounds: Cell disruption strategies for Rhodotorula'
Yashaswini Nagavara Nagaraj

15:00-15:10

'Integrated analysis of Yarrowia lipolytica bioprocesses for hydrocarbons valorization: linking cell structure, lipids, and enzymes production'
Marlene Lopes

15:10-15:40

Coffee break

15:40-16:50

THE YOUNG RESEARCHERS REPORTS
Chair: Vivien Measday & Maciej Wnuk

'A single-molecule approach to the study of protein aggregation in response to stress'
Linde Viaene

'Bioprospecting new yeast strains for application in lignocellulose-based biorefineries'
Julia Mourão Fernandes

'Motifs in the histone H3 and H4 and chromatin modifying factors are crucial to regulate the multifactorial zinc response pathway in Saccharomyces cerevisiae'
Rajshree Pal

'Histone mutations disrupt copper homeostasis impairing the Sec61-dependent protein translocation mechanism in Saccharomyces cerevisiae'
Santoshi Acharjee

'A new look at hexokinase from Yarrowia lipolytica: crystallographic and functional analysis'
Kacper Szymański

'Impact of yeast sequential inoculation strategies to diversify the aroma and flavour profiles of cider'
Siyamkele Solontsi

'OMICS analyses of the wine yeast Hanseniaspora guilliermondii to ethanol stress'
Diogo Santos

'Impact of glucose and propionic acid on even and odd chain fatty acid profiles of oleaginous yeasts'
Veronica Bonzanini

'Yarrowia lipolytica, dimorphic transition and lipid synthesis'
Alejandro Ordonez

'Unlocking the catalytic potential of yeast geranylgeranyl diphosphate synthase through metabolic-driven epistatic interactions'
Yueming Dong

'Transcription factors as tools of massive operation in engineering of industrial traits in Yarrowia lipolytica'
Maria Gorczyca

18:30-22:30

Conference dinner

09:00-10:40

YEASTS AS MOLECULAR FACTORIES II
Chair: Paola Branduardi & Rodrigo Ledesma-Amaro

09:00-09:20

'Yeast biodiversity and metabolic engineering for creating novel value chains in industrial biotechnology'
Paola Branduari

09:20-09:30

'The journey of red yeast Rhodotorula toruloides from laboratory to industrial production'
Ivana Marova

09:30-09:40

'Identification of novel secretion signals and screening of precision fermentation strains using a dual reporter system'
Parastoo Karimian

09:40-09:50

'In vivo promoter shuffling enables streamlined engineering of yeast production strains'
Lena Hochrein

09:50-10:00

'Synthetic communities of Yarrowia lipolytica for bioproduction'
Armand Bernard

10:00-10:10

'Toxic and useful: harnessing yeast killer toxins for product recovery'
Ankita Suri

10:10-10:20

'Metabolic engineering to bring progress to life™'
Paul Klaassen

10:20-10:40

TBA

10:40-11:00

'Confluence of parallel advances in yeast-based synthetic biology, bioinformational engineering and bioelectronics'
Isak S. Pretorius

11:00-11:30

Coffee break

11:30-13:50

CLOSING CEREMONY

11:30-12:20

'Systems biology of yeast metabolism'
Jens Nielsen

12:20-13:20

Awards ceremony

13:20-13:50

Closing remarks